In situations where doctors judge that there is a risk of harm to self or others, they may impose short involuntary hospitalization. In a network comparative meta-analysis of 15 antipsychotic drugs, clozapine was significantly more effective than all other drugs, although clozapine's heavily multimodal action may cause more side effects. Up to a third of people do not respond to initial antipsychotics, in which case the atypical antipsychotic clozapine may be used. The mainstay of treatment is antipsychotic medication, along with counseling, job training, and social rehabilitation. In 2015, an estimated 17,000 deaths were linked to schizophrenia. Compared to the general population, people with schizophrenia have a higher suicide rate (about 5% overall) and more physical health problems, leading to an average decrease in life expectancy by 20 years. Social problems such as long-term unemployment, poverty, homelessness, exploitation, and victimization are commonly correlated with schizophrenia. In some cases people may be repeatedly admitted to hospitals. The other half will have a lifelong impairment. Ībout half of those diagnosed with schizophrenia will have a significant improvement over the long term with no further relapses, and a small proportion of these will recover completely. Possible environmental factors include being raised in a city, cannabis use during adolescence, infections, the ages of a person's mother or father, and poor nutrition during pregnancy. Genetic factors include a variety of common and rare genetic variants. The likely causes of schizophrenia include genetic and environmental factors. Males are more often affected and on average have an earlier onset, although some large reviews have not found gender differences in the prevalence of the disorder. In 2017, there were an estimated 1.1 million new cases and in 2019 a total of 20 million cases globally. Ībout 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. To diagnose someone with schizophrenia, doctors are supposed to confirm that symptoms and functional impairment are present for six months ( DSM-5) or one month ( ICD-11). Besides observed behavior, doctors will also take a history that includes the person's reported experiences, and reports of others familiar with the person, when making a diagnosis. There is no objective diagnostic test the diagnosis is used to describe observed behavior that may stem from numerous different causes. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Major symptoms include hallucinations (typically hearing voices), delusions, paranoia, and disorganized thinking. Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. There are about 2.77 million new schizophrenia diagnoses every year worldwide. Substance use disorder, Huntington's disease, mood disorders ( bipolar disorder), autism, borderline personality disorder Ģ0 years shorter life expectancy Suicide, heart disease, lifestyle diseases įamily history, cannabis use in adolescence, problems during pregnancy, childhood adversity, birth in late winter or early spring, older father, being born or raised in a city īased on observed behavior, reported experiences, and reports of others familiar with the person Hallucinations (usually hearing voices), delusions, paranoia, confused thinking
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